Fracture Healing Research—Shift towards In Vitro Modeling?
نویسندگان
چکیده
منابع مشابه
Fracture healing
Those of us who have experienced a significant fracture likely recall first the pain of the injury, then we often focus our attention on the prospect of time in a cast or other form of extended immobilization. We imagine the discomfort and limitations that will ensue, and after all else settles down, we often wonder, “How strong are my bones anyway, and will I fracture again?” Nature, on the o...
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Purpose: To establish a rat mandibular fracture model and investigate the shortand long-term effects of recombinant parathyroid hormone (PTH 1-34) on mandibular fracture healing in rats. Materials and Methods: A controlled unilateral mandibular fracture was created surgically in 29 male Sprague-Dawley rats and then stabilized using an external fixation device. The rats were divided into 2 group...
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Background and objectives: Luteolin (3′,4′,5,7-tetrahydroxy flavone) is one of the most common flavones, which is naturally found in several edible plants and traditional medicine. It is known as a non-toxic compound with anti-inflammatory, antinociceptive, anticarcinogenic, antimutagenic, and antiangiogenic properties. Luteolin has antiproliferative activity against different ...
متن کاملMetaphyseal Fracture Healing
Most of what is known about fracture healing comes from studies of shaft fractures in long bones. In contrast, patients more often have fractures closer to the ends (metaphyses). Here most bone tissue has a spongy, cancellous structure different from the compact bone of the shaft. There is an increasing awareness that metaphyseal fractures heal differently. However, the more easily studied shaf...
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ژورنال
عنوان ژورنال: Biomedicines
سال: 2021
ISSN: 2227-9059
DOI: 10.3390/biomedicines9070748